Surgery Godfather-Chapter 1392 - 1051_2
Chapter 1392: Chapter 1051_2
The independent ward was fully equipped with various high-end rescue devices. Originally, it was meant to serve as a dedicated ICU for the Surgical Research Institute. The renovation and equipment were all set, but the staff had not yet been put in place, so it remained vacant for the time being. Now, it came in handy as an experimental ward for Sisi, to avoid placing extra pressure on the ICU doctors and nurses by having Sisi there.
"Is it okay for her to have such convulsions?" Dr. Jin asked again. After all, having been an orthopedics doctor for so many years, he had little experience with children’s high fever seizures and was somewhat worried.
Yang Ping reassured confidently, "Don’t worry, let her convulse with all this equipment here. We just need to strengthen the heart and lung monitoring, pay attention to replenishing fluids and energy, and we will help her pull through."
After saying this, Yang Ping lay down on the accompanying bed to sleep. Dr. Jin was very astute and reliable in his actions, so Yang Ping felt quite at ease with him. If it were some other young doctor, Yang Ping would certainly not rest assured. Lack of experience could easily lead to misjudgments and insufficient recognition and warning of potential risks.
Around four o’clock in the afternoon, Sisi’s temperature began to drop, indicating that the virus had gradually started to die in her body. The tug-of-war between the immune system and the virus had begun to tilt in favor of the immune system, with the virus showing signs of defeat.
This was good news. Not only was Sisi likely to survive from the brink of death, but there was also another very important point: the virus showed significant differences in its effects on the human body compared with the original virus. It was likely no longer the same type of virus, meaning that the addition of the K factor had completely altered the virus’s behavior.
It is now tentatively estimated that the K virus is a completely new virus to the human body, incapable of producing antibodies against it. The body can only rely on an excessive and broad immune response to fight it. This kind of resistance carries a high risk. If it’s not successful, the body could collapse. Fortunately, these viruses lack the ability to replicate. As each one dies, there are fewer left, so their combat power is very limited.
From the injection of the K virus to now, when there is a downward trend in temperature, nurses have drawn many blood samples from Sisi. These are to be used for various tests to dynamically monitor the changes in the body’s indicators under the influence of the virus.
In fact, some of the reagents used for examining these blood samples are also brand new, manufactured specifically for this particular experiment. Because existing diagnostic reagents could not detect many novel indicators, such as marker substances for these viruses.
It was uncertain whether the blood drawn contained any of the viruses that could be used for research, especially the investigation of whether there were mutations in the virus within the body. Since these viruses had no replicative ability, mutations would not be passed down and were difficult to capture.
After the decrease in body temperature, Sisi sweated profusely, soaking the entire bedsheets. The nurse changed the sheets and dressed Sisi in dry clothes, while also increasing the fluid replenishment to maintain a balance of fluids.
On the electrocardiogram monitor, the heart rate also began to decline slowly with the body temperature, allowing Yang Ping to temporarily breathe a sigh of relief.
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At Nandu Medical University, the virology laboratory and the digital medical laboratory were working intensely. They received the data from this experiment and immediately began to correct the K virus and the experiment itself.
Originally, the digital medical laboratory’s intelligent model had simulated the outcomes hundreds of thousands of times. The likelihood of such a high fever was extremely low, less than one in a hundred thousand. That such a low probability event had actually occurred with Sisi meant either she was unlucky to encounter this one-in-a-hundred-thousand chance, or the model’s prediction was erroneous and the actual probability of such a high-risk outcome was far greater than predicted by the model.
Of course, science cannot be left to chance, so Professor He and his team assumed the latter to be the case and began to check and improve their model.
The data from this experiment were extremely valuable; it was not from animal tests but direct clinical experiment data, which was hugely significant for the correction of the models.
Professor He’s team worked to improve their model, while Professor Zhang Zhiwei’s team was also busy. They began to further analyze the structure of the virus to determine the ideal location for implanting the K factor and what other changes might still be needed in the original virus’s genome. These were issues that needed to be reconsidered.
They had to re-analyze and summarize the structure of the virus, ideally using the data from this experiment to theoretically revise the implantation at each site.
Moreover, Professor Zhang’s team also sought out the K virus in the blood samples sent to them. Although this task was extremely challenging, as it was very difficult to find the virus in the blood by now, they still wanted to try. Because if they could find the virus, they could observe whether it mutated after entering the human body, whether there were any changes, and whether the implanted K factor was still functionally active.
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Sisi was in a state of cloudy consciousness, but with stable vital signs, giving Yang Ping great confidence.
He began to biopsy the liver and lung tumors in her body, precisely targeting with the guidance of navigational instruments to extract some tumor cells. These tumor cells were then taken for analysis under an electron microscope in the laboratory.
This would confirm whether the K virus had successfully infected the tumor cells, and if infection had occurred, whether they had successfully initiated the apoptosis program in the tumor cells. If the apoptosis program had begun, they needed to understand the process.
Such analysis had to be targeted specifically at tumor cells; there was no other way.
Yang Ping knew that although Sisi had just narrowly escaped death, whether she could truly be saved was still uncertain. Carrying out various biopsies now would undoubtedly exacerbate her injury, but if he didn’t seize the opportunity now for a biopsy, once the moment was missed, even if the virus infected the tumor cells, there would be no way to capture the authentic initial, mid, and terminal states of these tumor cells after infection.
To save her, they could not afford to be soft-hearted at this time; everything had to follow the principle of rationality.
Yang Ping biopsied every metastatic tumor that could be punctured, taking many samples back to the electron microscopy laboratory at Nandu Medical University. He wanted to observe them personally.
Under the electron microscope, Yang Ping searched through each sample one by one, which required immense patience. Due to the assault of the human immune system during the virus’s transport through the body, the number of viruses that successfully infected tumor cells was unknown.
The samples Yang Ping now had might be normal cells, or tumor cells that had not been infected because the infected cells might not even be sampled.
Yang Ping could only search manually sample by sample; this job could not be substituted by software models or artificial intelligence, as both software models and AI would have to be based on a doctor’s data. With these brand new experiments lacking any historical data to feed such models, they were useless.
After scanning through hundreds of microscope images, Yang Ping finally found an abnormal tumor cell and immediately took a separate picture of this cell.